Your Brain on Ketones…..

Ketones and ADHD/ADD/Anxietyon June 16, 2017Leave a Comment

How a High Fat Diet Can help the Brain Work Better:

The modern prescription of high carbohydrate, low fat diets and eating snacks between meals has coincided with an increase in obesity, diabetes, and and increase in the incidence of many mental health disorders, including depression, anxiety, and eating disorders. In addition, many of these disorders are striking the population at younger ages.

https://www.psychologytoday.com/blog/evolutionary-psychiatry/201104/your-brain-ketones

………… And what does it mean to have a ketogenic brain? Let’s examine neurotransmitters and brain energy more closely. Specifically, glutamate and GABA (5).

GABA is the major inhibitory neurotransmitter in the mammalian nervous system. Turns out, GABA is made from glutamate, which just happens to be the major excitatory neurotransmitter. You need them both, but we seem to get into trouble when have too much glutamate. Too much excitement in the brain means neurotoxicity, the extreme manifestation of which is seizures. But neurological diseases as varied as depression, bipolar disorder, migraines, ALS, and dementia have all been linked in some way to neurotoxicity.

Glutamate has several fates, rather like our old buddy tryptophan. It can become GABA (inhibitory), or aspartate (excitatory and, in excess, neurotoxic). Ketogenic diets seem to favor glutamate becoming GABA rather than aspartate. No one knows exactly why, but part of the reason has to do with how ketones are metabolized, and how ketosis favors using acetate (acetoacetate is one of the ketone bodies, after all) for fuel. Acetate becomes glutamine, an essential precursor for GABA…….

About drheather
I have been practicing alongside my husband, Dr. Ralph S. Cardin, for the past 12 years and have worked in the health care environment for over 29 years. Besides being a passionate practitioner, I am a proud mother of four beautiful boys. I am active in my church and my children’s school and enjoy cooking and exercising.

Speak Your Mind

If you want an image to show with your comment, you will need a gravatar